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Symbol
Name
ID
Egfr
epidermal growth factor receptor
MGI:95294
Phenotype annotations related to endocrine/exocrine glands
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Diabetes mellitus
Exocrine pancreatic insufficiency
Pancreatic adenocarcinoma
Disease(s) Associated with EGFR
pancreatic cancer

Mouse Phenotypes
abnormal exocrine pancreas morphology
abnormal submandibular gland branching morphogenesis
endocrine/exocrine gland phenotype
abnormal pancreatic beta cell morphology
disorganized pancreatic islets
abnormal gonadotroph morphology
decreased lactotroph cell number
decreased somatotroph cell number
small adenohypophysis
abnormal mammary gland morphology
abnormal pancreas morphology
small pancreas
abnormal lactation
Availability Mouse Genotype
Egfrtm1Rdk/Egfrtm1Rdk
Egfrwa2/Egfrwa2
Tg(Gh1-rtTA)4-3Jek/0
Tg(tetO-Egfr*)2-9Jek/0
Tg(Prl-tTA)6-5Jek/0
Tg(tetO-Egfr*)2-9Jek/0
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory